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Writer's pictureSandra A. Ho, MD

NSAID Allergy


Nonsteroidal anti-inflammatory drugs (NSAIDs) are a type of medication commonly used to reduce inflammation and relieve pain. While they are generally considered safe and effective, some people may experience an allergic reaction to NSAIDs.

An NSAID allergy can manifest in a variety of ways, including skin rashes, hives, difficulty breathing, and gastrointestinal symptoms such as abdominal pain and diarrhea. In severe cases, anaphylaxis, a life-threatening allergic reaction, may occur.

The severity of an NSAID allergy can range from mild to severe. Some people may experience a mild reaction, such as a skin rash, after taking NSAIDs for the first time. Others may have a more severe reaction, such as anaphylaxis, even after taking the same NSAID for a long period of time. The exact cause of an NSAID allergy is not fully understood, but it is thought to be related to the way the body's immune system responds to the medication. Some people may be more prone to developing an allergy due to their genetic makeup or a previous allergic reaction to a different medication. It is important to be aware of the potential for an NSAID allergy and to speak with a healthcare professional if you experience any symptoms after taking NSAIDs. If you have a history of allergies or have had a reaction to NSAIDs in the past, it is important to let your healthcare provider know before taking any new medication.

There are several alternatives to NSAIDs that may be effective for managing inflammation and pain. These include acetaminophen, which is a pain reliever that does not have anti-inflammatory properties, and corticosteroids, which are a type of medication that can reduce inflammation. If you have an NSAID allergy and need to take medication for pain or inflammation, it is important to work with your healthcare provider to find an alternative that is safe and effective for you. Your provider may recommend trying a different type of NSAID or a different class of medication altogether.

In conclusion, while NSAIDs are a widely used and effective medication for managing inflammation and pain, it is important to be aware of the potential for an allergic reaction. If you have an NSAID allergy or have had a reaction to these medications in the past, it is important to speak with a board-certified allergist and explore alternative treatment options.

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